FUNCTIONAL ANALYSIS OF THE CATHEPSIN-LIKE CYSTEINE PROTEASE GENES IN ADULT BRUGIA MALAYI USING RNA INTERFERENCE.

Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference.

Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion.Functional analysis of Caenorhabditis elegans cat

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High Fat Programming and Cardiovascular Disease

Programming is triggered through events during critical developmental phases that alter offspring health outcomes.High fat programming is defined as the maintenance on a high fat diet during fetal and/or early Clip postnatal life that induces metabolic and physiological alterations that compromise health.The maternal nutritional status, including t

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